Jasmine PRO
IMPROVED DRUG DELIVERY BY NOVEL POLYMER TECHNOLOGY
Poly(jasmine lactone), a patent-protected polymer, provides a new solution for increasing the solubility of poorly soluble drugs and facilitates the development of targeted and controlled drug delivery formulations. The advantages of poly(jasmine lactone) are its competitive drug-loading capacity and its favorable structure enabling easy attachment of stimuli-sensitive linkers for fabrication of polymer-drug conjugates.
Application Areas
Poly(jasmine lactone) is a versatile polymer with three main application areas
Solubility Enhancement
Poor aqueous solubility is a common concern in drug development. Learn more about how poly(jasmine lactone) can increase the solubility of poorly soluble drugs.
Targeted Drug Delivery
Targeting the drug to the disease site increases efficacy and decreases the toxicity. Easy-click chemistry of poly(jasmine lactone) enables the attachment of targeting linkers.
Nanotechnology-Based Drug Delivery
Possibilities to incorporate advantages of nanoparticles in drug formulations.
Jasmine PRO
Improved drug delivery is not a matter of science fiction
Jasmine PRO is an emerging Polymer Research Organization at Åbo Akademi University in Turku, Finland. In 2018, Kuldeep Bansal developed a novel polymer, poly(jasmine lactone), from monomers found in the jasmine flower to be used in advanced drug delivery.
Today at Jasmine PRO, our goal is to create a more efficient and effective way of delivering medication to patients, with the ultimate aim of improving patient outcomes. We are focused on improving existing pharmaceutical products as well as pipeline molecules and helping pharmaceutical companies solve their most challenging drug formulation problems.
We are on our journey as we strive to make a difference in the lives of patients around the world and to bring a technological breakthrough in the pharmaceutical field.
WHAT WE OFFER
Jasmine PRO will help improve the delivery of drugs
Poly(jasmine lactone) and its functionalities
Natural and Versatile
We have developed a novel drug delivery polymer that is derived from jasmine lactone, a natural compound found in jasmine flowers. We are on a mission to demonstrate that poly(jasmine lactone) possesses a potential to enhance the bioavailability and efficacy of drugs, decrease their adverse effects, and deliver them in a controlled and targeted manner.
Enhancing Solubility
Poly (jasmine lactone) can aid the solubilizing of poorly soluble drugs by implementing micellar solubilization or by developing amorphous solid dispersions.
Controlled and Targeted Drug Delivery
Poly(jasmine lactone) is a novel functional block copolymer with the ability to attach stimuli-sensitive and targeting ligands, forming polymer-drug conjugates (PDCs). These PDCs can provide highly targeted action by activation of the bound drug only in the desired localities, thus avoiding harmful side effects.
WHY CHOOSE US
Poly(jasmine lactone) possesses several advantages
Poly(jasmine lactone) and its functionalities
Patent-Protected
Patent granted in Finland for the synthesis and structure of poly(jasmine lactone). National patent application has been filed to the USA, Europe, and Japan (March 2022).
Patent ID: PCT/FI2020/050579
Safe
Cytotoxicity studies on mammalian cells suggests that the polymer is safe in working concentrations. Animal studies are currently ongoing to evaluate LD50 and other acute toxicity parameters.
Versatile
It offers endless functionalization possibilities due to the presence of double bonds on the polymer backbone.
THE TEAM
Our Visionary Team
Jessica Rosenholm
Co-Scientific Director
Turku, Finland
jessica.rosenholm@jasminepolymer.com
Carl-Eric Wilén
Co-Scientific Director
Turku, Finland
carl-eric.wilen@jasminepolymer.com
André-Gilles Le Gal
Business Lead
andre.le.gal@jasminepolymer.com
Kuldeep Bansal
Scientific Lead
Turku, Finland
kuldeep.bansal@jasminepolymer.com
Join our growing team!
ARTICLES & JOURNALS
Our Latest Publications
Learn more about our technology from peer-reviewed publications.
Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs
In this review manuscript, we have discussed the variety of nanocarriers, that are being utilized for improving aqueous solubility of drugs. Jasmine PRO technology has also been demonstrated its applicability to achieve high drug solubility and cited well in this manuscript. Our technology can be utilized to formulate polymeric micelles and polymer-drug conjugates with high drug loading efficiency.
Functional Block Copolymer Micelles based on Poly (Jasmine Lactone) for Improving the Loading Efficiency of Weakly Basic Drugs
In this study, we used our novel amphiphilic block copolymer mPEG-b-PJL, made from renewable monomer feedstock and polyethylene glycol, to provide higher drug loading efficiency.
Evaluation of Solubilizing Potential of Functional Poly(Jasmine Lactone) Micelles for Hydrophobic Drugs: A Comparison With Commercially Available Polymers
Despite several solubilizing options on the market, high aqueous solubilization of poorly soluble drugs still remains a challenge to be overcome. With that objective in mind, we conducted a study where we compared the solubilization capacity of two commercially available polymers, i.e., Soluplus® and the amphiphilic block copolymer of poly(lactic acid) (PLA) with poly(ethylene glycol) (PEG), mPEG-b-PLA, with that of poly(jasmine lactone)-based polymers.
Significance of Polymers with “Allyl” Functionality in Biomedicine: An Emerging Class of Functional Polymers
In this review article, we have highlighted the significance of a unique class of polymers called allyl-terminated polymers. Our polymer, poly(jasmine lactone), belongs to this group of functional polymers.
Synthesis and Evaluation of Novel Functional Polymers Derived from Renewable Jasmine Lactone for Stimuli-Responsive Drug Delivery
In this paper, we have reported for the very first time the synthesis and one of the biomedical applications of our novel block copolymer (mPEG-b-PJL) made from renewable jasmine lactone, which has great potential to be used as a polymer in advanced drug delivery systems.
GET IN TOUCH
Don’t hesitate to contact us
Are you interested in learning more, want to join our team, or have a specific use case in mind? Let’s talk!
Providing a new solution for solubility enhancement, targeted drug delivery, and nanoparticle-mediated drug delivery.
Contact
+358 46 566 3258